CINTACS Newsletter of the Cincinnati Section of the  American Chemical Society  Vol. 38, No. 3 - November 2000

CINTACS is published nine times a year (September through May) by the Cincinnati Section of the American Chemical Society. All changes of address should be sent to Emel Yakali at Raymond Walters College, 9555 Plainfield Road, Cincinnati, OH 45236, phone 745-5686, FAX 745-5767, or email mc.acs@uc.edu.

SUBMISSION DEADLINES

The submission deadline for the January  issue is December 1, 2000. Electronic submission is strongly preferred, except for original photos. All materials should be sent to:

Dr. Bruce Ault
Department of Chemistry
University of Cincinnati
Cincinnati, OH 45221
Phone: 513-556-9238
FAX: 513-556-9239
E-mail: bruce.ault@uc.edu

Greeting’s! By the time you read this, we will be fully into our section program. The next few months will be a busy time for our section with lots of opportunities to participate in a variety of programs. This month’s section meeting offers to be as stimulating as ever with the Oesper Award and Banquet. Please note, this meeting will feature an informal poster presentation by students and members of the Cincinnati ACS Section. This forum is a great opportunity to identify common interests and build new scientific relationships. For those who would still like to participate in this poster session, there still is time. Please contact Jeanette Krause-Bauer (jeanette.krause@uc.edu, (513) 556-9226) at the University of Cincinnati for your needs and information about the poster session.

This month we will also celebrate National Chemistry Week. As of this writing, the science demos at the twenty or so libraries and other activities have not occurred. But I know they will be successful. I would like to thank Soumya Patnaik and Lisa Clapp from the Women’s Chemist Committee for all their hard work in organizing this affair.  I would further like to thank all the member volunteers for their hard work and participation. A special thanks goes to the Cognis Corporation and the National ASC for their generous sponsorship and donation

We have finalized our Joint ACS, AIChE and AOCS Meeting in December. Dr. P. Gary Eller from Los Alamos National Laboratories will give a presentation titled “What Do We Do With 1000 Tons of Plutonium?” Should be an interesting evening. By the way, Gary claims to be some kind of a fisherman. I told him to bring pictures.
Again, I would like to remind you to nominate your choices for Chemist, Research Assistant, High School Teacher, Middle School Teacher and Elementary School Teacher of the Year Award. The Awards Chair, Tim Cassady; tim.cassady@cognis-us.com  can be contacted for specifics. Nominations should be into the Awards Chair by the evening of November 16th at the Oesper Banquet.

The role of Chair-Elect is a very active one prior to the year of chairmanship. In particular, Hank Greeb, Chair-Elect will spend the next many months planning the next years budget, primary speakers, meeting sites, and format. Additionally, Hank will sacrifice a weekend to participate in a training session put on by the American Chemical Society. In this training session a wealth of information on topics ranging from successful meeting and section organizing tips to the workings and activities of the National ACS are transmitted. These sessions also offer our Chair-Elect an opportunity to interact and compare notes with other in-coming chairs from around the country. Comments and ideas for next years programs and activities can be directed to Chair-Elect Hank Greeb (385-8363, hgreeb@one.net).

I continue to look forward to working with the membership this year and please do not hesitate to contact me with suggestions and desires for additional involvement. Regards to all.   Come to the November meeting.

Rick Fayter - Cognis Corporation - (513) 482-3156 - Rick.fayter@cognis-us.com

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About the Speaker

Albert S. Mildvan. Born 1932.  A.B., Chemistry, University of Pennsylvania (1953), M.D., Johns Hopkins School of Medicine (1957).  Medical Intern, Baltimore City Hospitals (1957-8), Postdoctoral Fellow at N.I.H., Cambridge University, UK, and University of Pennsylvania (1958-1965).  Faculty, University of Pennsylvania and staff member Institute for Cancer Research, Fox Chase (1965-1981).  Professor of Biological Chemistry/Chemistry, Johns Hopkins School of Medicine (1981-present).  Number of publications, 248.  Current research: application of kinetic and magnetic resonance methods to studies of enzyme mechanisms.

Mildvan's banquet talk, entitled "Experiences in Mildred Cohn's Laboratory", will describe his scientific, sociological, and humanistic memories and those of other students, fellows, and faculty members who were part of Mildred Cohn's magnetic resonance group in the Johnson Research Foundation, between 1963 and 1967.
 

About the Awardee

Mildred Cohn was born in New York City on July 12, 1913.  Professor Cohn has been a pioneer in several important areas of biological research such as using isotopes to investigate metabolic processes and enzyme mechanisms and applying NMR and EPR to investigate metabolism and metabolic intermediates.  More generally, her work has had impact upon research areas ranging from cancer to biological NMR.  Her scientific contributions to these areas resulted in numerous awards and honors including: The American Chemical Society Garvan Medal (1963), The Franklin Institute Cresson Medal (1975), the National Medal of Science (1982), The Magnetic Resonance in Biology Founders Medal (1994) and The Protein Society Stein-Moore Award (1997).  In 1971, she was elected to membership in The National Academy of Sciences.

      Her educational background includes a B.A. from Hunter College and a Ph.D. from Columbia University.  She has held faculty positions at Washington University School of Medicine, The Institute for Cancer Research at Fox Chase Cancer Center and the University of Pennsylvania School of Medicine.  Professor Cohn is currently Benjamin Rush Professor Emerita of Physiological Chemistry at the University of Pennsylvania. Currently, her research interest involves investigation of metabolites as potential anti-cancer agents in tumors as monitored by in vivo NMR and other techniques.
 

The annual poster session for the Cincinnati Section of the American Chemical Society will take place prior to the Oesper Award Banquet on Thursday, Nov. 16, 2000.  All members of the section are welcome to present posters at this session (within space limitations).  Members interested in presenting a poster should submit the title to Jeanette Krause-Bauer, at Jeanette.Krause@uc.edu or 556-9226 no later than Friday, November 3, for inclusion in the program.  Questions should also be directed to Jeanette.  Please note:  you do not need to attend the banquet in order to present a poster.

The Educators’ Discussion Group is holding an exciting evening of chemical demonstrations on Wednesday, January 31, 2001 at the Seven Hills School at 5400 Red Bank Road. Experience the Will o’ the Wisp and flame tests done to the Rainbow Connection. Ride into a chemical sunset to the tune of Happy Trails. Linda Ford will host the evening and perform these three favorite demonstrations. She is actively seeking other teachers to share in the fun. A social time with light refreshments will begin at 6:30 PM. The first demonstration will be scheduled for 7 PM. The evening will draw to an end at 8:30. Linda guarantees that everyone in attendance will drive home humming Blue Moon! What a nice evening to bring a new colleague! Have you ever thought to invite the physical science teachers from your junior high or middle school programs?

Directions to Seven Hills: Exit Interstate 71 at Red Bank Road and travel east (the only choice you are given) to the first traffic light. Turn right onto Duck Creek and start up the hill but be ready to make the quick first right onto Old Red Bank Road. Travel the distance of about 3 city blocks and you will see the school on your right. Pull into the driveway and find a place to park. Then follow the signs to the chemistry lab. Linda can be reached at 272-5360 or linda.ford@7hills.org.
 

9:00 - 9:40 a.m.
June Taylor, St. Jude Children’s Research Hospital
“Still at 60MHz After all These Years”

9:45 - 10:25 a.m.
George Reed, Univ. of Wisconsin-Madison
“Radical Intermediates and Radical Mechanisms in Enzymology”

Morning Coffee Break

10:40 - 11:20 a.m.
Alan McLaughlin, National Inst. of Health
“In Vivo 17O MR Studies of the Rate of  Cerebral Oxygen Consumption”

11:25 - 12:05 p.m.
Paul Boyer, Univ. of California, Los Angeles
“A Research Journey with ATP Synthase”

Lunch (Reservations required; Chef’s choice buffet)
Cost $12; Students $6
12:15 - 1:45 p.m

1:45 - 2:25 p.m.
Eileen Jaffe, Fox Chase Cancer Center
Institute for Cancer Research
“Asymmetry and Diversity in the Metals of Pyrrole Biosynthesis”

2:30 - 3:10 p.m.
Al Mildvan, Johns Hopkins University School of Medicine
“Solution, Structure and Mechanism of the MutT Pyrophosphohydrolase”

3:15 - 3:55 p.m.
B. D. Nageswara Rao, IUPUI
“Mechanistic Differentiation of ATP-Utilizing Enzymes: Answers to Mildred Cohn’s Questions Remain Elusive”

Afternoon Coffee Break

4:10 - 4:50 p.m.
Tom James, Univ. of California, San Francisco
“Three-dimensional RNA Structure as a Basis for Drug Discovery”

4:55 - 5:35 p.m.

Professor Mildred Cohn
University of Pennsylvania School of Medicine

OESPER AWARD LECTURE
“Chemical Parsimony in Living Organisms: The Case of ATP”

For further information contact:

Kim Carey                                 
Department of Chemistry
University of Cincinnati
Cincinnati, Ohio 45221-0172
(513) 556-0293
careykr@email.uc.edu                                         

Pearl Tsang
Department of Chemistry
University of Cincinnati
Cincinnati, Ohio 45221-0172
(513) 556-2301
pearl.tsang@uc.edu

Visit our web site at: http://www.che.uc.edu/Chemistry/seminar.html

Formatted and uploaded March 16, 2001, by acs@www.che.uc.edu